Long-term memories made with meaningful information

Long-term memories made with meaningful information

When trying to memorize information, it is better to relate it to something meaningful rather than repeat it again and again to make it stick, according to a recent Baycrest Health Sciences study published in NeuroImage.

“When we are learning new information, our brain has two different ways to remember the material for a short period of time, either by mentally rehearsing the sounds of the words or thinking about the meaning of the words,” says Dr. Jed Meltzer, lead author and neurorehabilitation scientist at Baycrest’s Rotman Research Institute. “Both strategies create good short-term memory, but focusing on the meaning is more effective for retaining the information later on. Here’s a case where working harder does not mean better.”

Past studies have looked at repetition to create short-term memories, but these findings suggest that using the word’s meaning will help “transfer” memories from the short-term to the long-term, says Dr. Meltzer. This finding is consistent with the strategies used by the world’s top memory champions, who create stories rich with meaning to remember random information, such as the order of a deck of cards.

Through this work, researchers were able to pinpoint the different parts of the brain involved in creating the two types of short-term memories.

“This finding shows that there are multiple brain mechanisms supporting short-term memory, whether it’s remembering information based on sound or meaning,” says Dr. Meltzer, who is also a psychology professor at the University of Toronto. “When people have brain damage from stroke or dementia, one of the mechanisms may be disrupted. People could learn to compensate for this by relying on an alternate method to form short-term memories.”

For example, people who have trouble remembering things could carry a pad and rehearse the information until they have a chance to write it down, he adds.

The study recorded the brain waves of 25 healthy adults as they listened to sentences and word lists. Participants were asked to hold the information in their short-term memory over several seconds, and then recite it back, while their brain waves were recorded. Participants were then taken to a testing room to see if they could recall the information that had been heard. Through the brain scans, researchers identified brain activity related to memorizing through sound and meaning.

As next steps, Dr. Meltzer will use these findings to explore targeted brain stimulation that could boost the short-term memory of stroke patients. Additional funding would support the exploration of which types of memory are best treated by current drugs or brain stimulation and how these can be improved.

Story Source: Baycrest Centre for Geriatric Care. “Long-term memories made with meaningful information.” ScienceDaily. ScienceDaily, 20 June 2017. <www.sciencedaily.com/releases/2017/06/170620140624.htm>.

Clinical benefit of clot retrieval now proven up to 24 hours after major ischemic stroke

Clinical benefit of clot retrieval now proven up to 24 hours after major ischemic stroke

Results of an international, randomized controlled research study show that mechanical thrombectomy, which is an endovascular treatment to remove a stroke-causing blood clot in the brain, is effective in some patients even when performed within 6 to 24 hours after a stroke.

The findings of the study were presented in late May at the European Stroke Organization Conference 2017 in Prague. Rush University Medical Center is the only Illinois site, one of seven sites in the U.S, and one of only 22 sites in the world to participate in the international study called the DAWN trial where severe stroke patients underwent a thrombectomy after the six hour time window. (more…)

Long-term memories made with meaningful information

A SMARTer way to discover new stroke treatments

A sequential multiple assignment randomized (SMART) trial allows researchers to test two hypotheses at once.

The new trial method is being used in clinical trials across the industry.

“SMART trials allow you to get to two questions at once and can potentially be more efficient,” says William Meurer, M.D., associate professor of emergency medicine and neurology at Michigan Medicine and a member of the Michigan Center for Integrative Research in Critical Care. “You may find answers you wouldn’t normally find using a normal trial design.”

Meurer is the lead author on a study published in the Journal of Stroke and Cerebrovascular Diseases that investigated if the trial design could be used specifically to study stroke treatment.

“In stroke, we are often treating the patient with a tissue plasminogen activator drug upfront to dissolve a blood clot in the brain,” Meurer says. “Sometimes, that blood clot doesn’t dissolve. What do you do next?” (more…)

Is educational attainment associated with lifetime risk of cardiovascular disease?

Is educational attainment associated with lifetime risk of cardiovascular disease?

Men and women with the lowest education level had higher lifetime risks of cardiovascular disease than those with the highest education level, according to a new study published by JAMA Internal Medicine.

One of the most important socioeconomic factors contributing to cardiovascular disease (CVD) is educational inequality. Calculating the lifetime risk of CVD according to educational levels is one way to convey the importance of educational attainment. (more…)

Stroke rates rising among younger adults: Report

Stroke rates rising among younger adults: Report

CTVNews.ca Staff
Published Wednesday, June 7, 2017 12:21PM EDT
Last Updated Wednesday, June 7, 2017 9:29PM EDT

A new report warns that the rates of stroke are increasing among Canadian young adults faster than among older adults.

The risk of a stroke increases with age, which is why 80 per cent of all strokes happen to those over 60. But an increasing percentage of hospital admissions for stroke are occurring among patients between the ages of 20 and 59, the Heart & Stroke 2017 Stroke Report reveals. (more…)