New mindset in the search for stroke therapies

New mindset in the search for stroke therapies

UNSW researchers have identified a promising new avenue to explore in the search for stroke treatments, after translating findings from Alzheimer’s disease.

The study published in Nature Communications finds that mice deficient in tau, a protein within brain cells (neurons), are significantly protected from excitotoxic brain damage after experimental stroke. (more…)

New mindset in the search for stroke therapies

Seven steps to keep your brain healthy from childhood to old age

A healthy lifestyle benefits your brain as much as the rest of your body — and may lessen the risk of cognitive decline (a loss of the ability to think well) as you age, according to a new advisory from the American Heart Association/American Stroke Association.

Both the heart and brain need adequate blood flow, but in many people, blood vessels slowly become narrowed or blocked over the course of their life, a disease process known as atherosclerosis, the cause of many heart attacks and strokes. Many risk factors for atherosclerosis can be modified by following a healthy diet, getting enough physical activity, avoiding tobacco products and other strategies. (more…)

New mindset in the search for stroke therapies

Irish Heart’s ‘Heart Month’ – Life begins at 40 so don’t let stroke stop it

This September Irish Heart’s ‘Heart Month’ campaign will focus on Stroke Prevention.

Over 2,000 people under 65 have a stroke each year but the good news is that by making small changes to your lifestyle today you can reduce your chances of having a stroke now and in the future.
Make time for a blood pressure check now and find out what you need to do to avoid stroke at www.irishheart.ie (more…)

New mindset in the search for stroke therapies

Reducing inflammation without lowering cholesterol cuts risk of cardiovascular events

Inflammatory hypothesis confirmed: Landmark randomized clinical trial of high-risk patients finds that a drug targeting inflammation reduced risk of major adverse cardiovascular events.

Investigators from Brigham and Women’s Hospital today announced results of a clinical trial culminating from 25 years of cardiovascular research work. At the European Society of Cardiology meeting and in a paper published simultaneously in the New England Journal of Medicine, Paul M. Ridker, MD, director of the Center for Cardiovascular Disease Prevention at BWH, and colleagues presented findings from CANTOS (Canakinumab Anti-inflammatory Thrombosis Outcomes Study), a trial designed to test whether reducing inflammation among people who have had a prior heart attack can reduce risk of another cardiovascular event in the future. The team reports a significant reduction in risk of recurrent heart attacks, strokes and cardiovascular death among participants who received a targeted anti-inflammatory drug that lowered inflammation but had no effects on cholesterol. (more…)

Poor sleep is associated with ischemic heart disease and stroke

Poor sleep is associated with ischemic heart disease and stroke

Poor sleep is associated with ischaemic heart disease and stroke, according to research presented at ESC Congress 2017 in Barcelona, Spain. The observational study in nearly 13,000 people revealed different patterns of sleep disturbance between the two conditions, with ischaemic heart disease being linked to shorter sleep and brief moments of waking up.

“Poor sleep is associated with cardiovascular diseases such as ischaemic heart disease and stroke but the kind of sleep disturbances that are most risky is not well documented,” said lead researcher Dr Nobuo Sasaki, of the Hiroshima Atomic Bomb Casualty Council, Japan. “‘Poor sleep’ includes too short or too long sleep, difficulty falling asleep, and difficulty maintaining sleep.” (more…)